Exploring the Diagnostic Test Accuracy of MicroRNAs as Potential Biomarkers for Glioblastoma: Systematic Review and Meta-Analysis
miRNAs, especially miR-21, demonstrate significant utility for diagnosis of GBM and for ruling out diagnosis in patients who do not have GBM. These findings support the further development of miRNA-based liquid biopsies for GBM diagnosis with emphasis on clinical validation and standardization of technique.
Authors
- Jeffrey Zuccato (ORCID: https://orcid.org/0000-0001-5418-8238)
- Jennifer Ho
- Shannan Bialek
- James Battiste
- Christopher S. Graffeo (ORCID: https://orcid.org/0000-0001-5314-1067)
- Taylor Niznik (ORCID: https://orcid.org/0009-0007-3658-3446)
- Ian F. Dunn (ORCID: https://orcid.org/0000-0003-0275-6736)
- Abigail York
- Marianne Kimmell
Institutions
- University of Oklahoma Health Sciences Center (US)
- University of Oklahoma (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1227/neu.0000000000003813
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00