Correlation of Dermatopathologic Findings and Autoantibody Subtypes in Dermatomyositis

Variability in skin biopsy findings from dermatomyositis patients with specific autoantibodies is limited. Perivascular inflammation without interface change and an absence of dermal mucin may be more common in patients with nuclear matrix protein 2 and TIF1γ autoantibodies, respectively. These observations may aid diagnosis in cases with atypical histologic features.

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Publication Details

Journal
American Journal of Dermatopathology
Published
2025-10-22
DOI
https://doi.org/10.1097/dad.0000000000003158
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
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article

Correlation of Dermatopathologic Findings and Autoantibody Subtypes in Dermatomyositis

Anna Brusch, Sarah M. Russell, Nima Mesbah Ardakani, Nathan T. Harvey et al.
American Journal of Dermatopathology
Inflammatory Myopathies and Dermatomyositis
article

Correlation of Dermatopathologic Findings and Autoantibody Subtypes in Dermatomyositis

Anna Brusch, Sarah M. Russell, Nima Mesbah Ardakani, Nathan T. Harvey, Benjamin A. Wood
article en

Abstract

Variability in skin biopsy findings from dermatomyositis patients with specific autoantibodies is limited. Perivascular inflammation without interface change and an absence of dermal mucin may be more common in patients with nuclear matrix protein 2 and TIF1γ autoantibodies, respectively. These observations may aid diagnosis in cases with atypical histologic features.

American Journal of DermatopathologyVol. 48(2)
The University of Western Australia (AU), Sir Charles Gairdner Hospital (AU), Perron Institute for Neurological and Translational Science (AU), Pathwest Laboratory Medicine (AU), The University of Notre Dame Australia (AU)
Openalex Percentile: Top 59%
Inflammatory Myopathies and Dermatomyositis
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Correlation of Dermatopathologic Findings and Autoantibody Subtypes in Dermatomyositis — Anna Brusch, Sarah M. Russell, et al. · American Journal of Dermatopathology (2025) | TGRS Research Map | TGRS