Investigating the relationship between intestinal microbiota and Th1/Th2/Th17 imbalance in subclinical hypothyroidism during the first half of pregnancy: a multi-omics approach
In the first half of pregnancy, patients with SCH may experience intestinal microbiota disorder, characterized by increased levels of Faecalibacterium prausnitzii and decreased levels of Bacteroides uniformis, at the same time, it was accompanied by an increase in TG synthesis and a Th1/Th2/Th17 imbalance, these factors may be involved in the occurrence of SCH during pregnancy.
Authors
- Yajuan Xu (ORCID: https://orcid.org/0000-0003-0819-1369)
- Zongzong Sun (ORCID: https://orcid.org/0000-0003-2280-5945)
- Yanjie Ban (ORCID: https://orcid.org/0000-0002-2204-769X)
- Yixin Wang (ORCID: https://orcid.org/0000-0003-4324-2408)
- Jingjing Li (ORCID: https://orcid.org/0000-0003-0614-7698)
- Miao Zhang (ORCID: https://orcid.org/0000-0002-4242-005X)
- Chenchen Zhang (ORCID: https://orcid.org/0000-0001-8563-5002)
- Pengkun Lin
Institutions
- Third Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1186/s13099-025-00743-y
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Zhengzhou University