Breaking the link between morphology and potency for mESCs
These results provide evidence that the domed morphology and potency can be uncoupled and suggest that domed structure is not a pre-requisite for acquiring and maintaining naïve pluripotency.
Authors
- Tao Huang (ORCID: https://orcid.org/0000-0002-2583-7806)
- Duanqing Pei (ORCID: https://orcid.org/0000-0002-5222-014X)
- Zechuan Liang (ORCID: https://orcid.org/0009-0004-4292-6992)
- Ziwei Zhai (ORCID: https://orcid.org/0000-0002-8892-5491)
- Wei Shan Li (ORCID: https://orcid.org/0000-0001-7458-2590)
- Xiaomin Wang (ORCID: https://orcid.org/0000-0002-7907-4357)
- Zhaoyi Ma
- Pengli Li (ORCID: https://orcid.org/0000-0002-5878-7681)
- Junqi Kuang (ORCID: https://orcid.org/0000-0003-2681-7580)
- Yu Fu (ORCID: https://orcid.org/0000-0002-5495-2635)
- Yixin Fan (ORCID: https://orcid.org/0000-0002-0529-3768)
Institutions
- Chinese Academy of Sciences (CN)
- Guangzhou Institutes of Biomedicine and Health (CN)
- Westlake University (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Cell & Bioscience
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1186/s13578-025-01497-5
- Citations
- 1
- Primary Topic
- Pluripotent Stem Cells Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Westlake University
- National Natural Science Foundation of China
- Innovation and Technology Commission