Prevention of postpartum hemorrhage in moderate and high‐risk patients: Addition of prophylactic misoprostol

Dual agent prophylaxis with oxytocin and misoprostol immediately after delivery was associated with a significant reduction in total blood loss, PPH rates, and composite morbidity compared to oxytocin only prophylaxis in patients undergoing cesarean birth. Prospective studies are warranted to assess replicability and safety.

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Publication Details

Journal
International Journal of Gynecology & Obstetrics
Published
2025-10-23
DOI
https://doi.org/10.1002/ijgo.70541
Primary Topic
Maternal and fetal healthcare
Type
article
Field-Weighted Citation Impact
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article

Prevention of postpartum hemorrhage in moderate and high‐risk patients: Addition of prophylactic misoprostol

Ashlesha K. Dayal, Rosalyn Chan‐Akeley, Shai Bejerano, Daniel W. Skupski et al.
International Journal of Gynecology & Obstetrics
Maternal and fetal healthcare
article

Prevention of postpartum hemorrhage in moderate and high‐risk patients: Addition of prophylactic misoprostol

Ashlesha K. Dayal, Rosalyn Chan‐Akeley, Shai Bejerano, Daniel W. Skupski, Dena Goffman, Liping Lü, Dinakar Velagala
article en

Abstract

Dual agent prophylaxis with oxytocin and misoprostol immediately after delivery was associated with a significant reduction in total blood loss, PPH rates, and composite morbidity compared to oxytocin only prophylaxis in patients undergoing cesarean birth. Prospective studies are warranted to assess replicability and safety.

International Journal of Gynecology & ObstetricsVol. 173(1)
Cornell University (US), Columbia University Irving Medical Center (US), Texas Health Dallas (US), New York Hospital Queens (US), Weill Cornell Medicine (US), Columbia University (US)
Openalex Percentile: Top 57%
Maternal and fetal healthcare
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Prevention of postpartum hemorrhage in moderate and high‐risk patients: Addition of prophylactic misoprostol — Ashlesha K. Dayal, Rosalyn Chan‐Akeley, et al. · International Journal of Gynecology & Obstetrics (2025) | TGRS Research Map | TGRS