Posaconazole enteral tube administration in adults: pharmacokinetic target attainment of oral suspension compared with crushed delayed-release tablet
With EFT administration, crushed posaconazole DR tablets were associated with a greater likelihood of achieving therapeutic concentrations compared with IR suspension. The optimal technique for administering crushed DR tablets to prevent EFT complications warrants investigation.
Authors
- Ryan W. Stevens (ORCID: https://orcid.org/0000-0002-5050-6689)
- Dan Ilges (ORCID: https://orcid.org/0000-0003-0778-3901)
- Tanner M Johnson (ORCID: https://orcid.org/0000-0002-9181-8347)
- Patrick M. Wieruszewski (ORCID: https://orcid.org/0000-0002-5871-5186)
- John C. Robinson (ORCID: https://orcid.org/0009-0004-8226-1884)
- Kristin Cole (ORCID: https://orcid.org/0000-0002-8783-0191)
- Casey O’Connell
- Nirjan Bhattarai (ORCID: https://orcid.org/0009-0002-7994-4209)
Institutions
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic Hospital (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1093/jac/dkaf396
- Primary Topic
- Clinical Nutrition and Gastroenterology
- Type
- article
- Field-Weighted Citation Impact
- 0.00