Donor-Derived Cell-Free DNA in Antibody-Mediated Rejection
The authors document significant context dependent variability of AMR incidence and the utility of dd-cfDNA in predicting biopsy yield. These data complement prior studies on the interpretation of peripheral gene expression profiling and dd-cfDNA for rejection monitoring and should further obviate the need for surveillance biopsies. (Surveillance HeartCare Outcomes Registry [SHORE]; NCT03695601).
Authors
- Shelley Hall (ORCID: https://orcid.org/0000-0002-4894-396X)
- Kiran Kaur Khush (ORCID: https://orcid.org/0000-0001-9697-5926)
- Amin Yehya (ORCID: https://orcid.org/0000-0001-5947-4778)
- Palak Shah (ORCID: https://orcid.org/0000-0001-8175-168X)
- K. Oreschak
- Richard Kar-Hang Cheng (ORCID: https://orcid.org/0000-0001-5994-5998)
- Kevin G. Pinney (ORCID: https://orcid.org/0000-0003-1262-8631)
- Sean Pinney (ORCID: https://orcid.org/0000-0002-0268-7817)
- Marcus A. Urey (ORCID: https://orcid.org/0000-0001-8311-5003)
- Jeffrey J. Teuteberg (ORCID: https://orcid.org/0000-0002-8342-3222)
- Christopher R. Ensor (ORCID: https://orcid.org/0000-0003-0990-1406)
- Jeremy Kobulnik (ORCID: https://orcid.org/0000-0002-5417-2866)
- Paul Kim (ORCID: https://orcid.org/0000-0002-1755-6182)
- Steve Fan
- Amit H Alam
Institutions
- University of Washington (US)
- Veterans Health Administration (US)
- Inova Fairfax Hospital (US)
- Baylor University Medical Center (US)
- University of California San Diego (US)
- NYU Langone Health (US)
- Cancer Research And Biostatistics (US)
- Mount Sinai Hospital (US)
- Sentara Heart Hospital (US)
- New York University (US)
- Stanford University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- JACC Heart Failure
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1016/j.jchf.2025.102716
- Citations
- 3
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.96