Network analysis of burnout, depression, and anxiety with occupational and personal outcomes among clinical nurses in China

Chinese nurses face staff shortages and heavy workloads, leading to increased depression, anxiety, and burnout. This study aimed to examine the symptom network of burnout, depression, and anxiety and its associations with negative personal and occupational outcomes among Chinese nurses. A total of 2092 nurses were recruited through snowball sampling. Burnout, depression, and anxiety were assessed using the two single-item burnout measures, Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder Scale-7 (GAD-7), respectively. Adverse outcomes, including low quality of life (QOL), suicidal ideation (SI), turnover intention, and medical errors, were also assessed. The network was estimated via the EBICglasso model, and centrality indices and bridge centrality indices were calculated to identify central and bridge symptoms, respectively. The prevalence of depression, anxiety, burnout, low QOL, medical error, turnover intention, and SI was 30.1%, 16.5%, 26.4%, 34.4%, 16.1%, 26.0%, and 26.5%, respectively. Results showed that GAD2 (Uncontrollable worry) was the most central symptom, whereas emotional exhaustion (EX), PHQ8 (Motor), and PHQ4 (Fatigue) were bridge symptoms. Depersonalization (DP) was most strongly associated with adverse work outcomes, and EX was the strongest predictor of poor QOL. The findings highlight the need for early detection and intervention for burnout to mitigate negative impacts.

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Publication Details

Journal
Scientific Reports
Published
2025-10-23
DOI
https://doi.org/10.1038/s41598-025-20865-2
Primary Topic
Mental Health Research Topics
Type
article
Field-Weighted Citation Impact
0.00

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article

Network analysis of burnout, depression, and anxiety with occupational and personal outcomes among clinical nurses in China

Huixue Xu, Tieqiao Liu, Peizhen Li, Peng Pu et al.
Scientific Reports
Mental Health Research Topics
article

Network analysis of burnout, depression, and anxiety with occupational and personal outcomes among clinical nurses in China

Huixue Xu, Tieqiao Liu, Peizhen Li, Peng Pu, Qiuxia Wu, Yi‐Yuan Tang, Xin Wang, Liyan Liu, Zejun Li, Kewen Yan
article en

Abstract

Chinese nurses face staff shortages and heavy workloads, leading to increased depression, anxiety, and burnout. This study aimed to examine the symptom network of burnout, depression, and anxiety and its associations with negative personal and occupational outcomes among Chinese nurses. A total of 2092 nurses were recruited through snowball sampling. Burnout, depression, and anxiety were assessed using the two single-item burnout measures, Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder Scale-7 (GAD-7), respectively. Adverse outcomes, including low quality of life (QOL), suicidal ideation (SI), turnover intention, and medical errors, were also assessed. The network was estimated via the EBICglasso model, and centrality indices and bridge centrality indices were calculated to identify central and bridge symptoms, respectively. The prevalence of depression, anxiety, burnout, low QOL, medical error, turnover intention, and SI was 30.1%, 16.5%, 26.4%, 34.4%, 16.1%, 26.0%, and 26.5%, respectively. Results showed that GAD2 (Uncontrollable worry) was the most central symptom, whereas emotional exhaustion (EX), PHQ8 (Motor), and PHQ4 (Fatigue) were bridge symptoms. Depersonalization (DP) was most strongly associated with adverse work outcomes, and EX was the strongest predictor of poor QOL. The findings highlight the need for early detection and intervention for burnout to mitigate negative impacts.

Scientific ReportsVol. 15(1)
Central South University (CN), Sir Run Run Shaw Hospital (CN), Second Xiangya Hospital of Central South University (CN), Third People's Hospital of Yunnan Province (CN), Arizona State University (US), Zhejiang University (CN)
Xiangya Hospital, Central South University
Openalex Percentile: Top 69%
Mental Health Research Topics
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