The Influence of GLP-1 Agonists on Human Mesenchymal Stem Cells: A Systematic Review
Glucagon-like peptide-1 receptor agonists modulate key pathways in human mesenchymal stem cells to influence survival, differentiation, and metabolic function, suggesting promising therapeutic potential beyond glycemic control. However, heterogeneous experimental designs and limited translational data necessitate further standardized and in vivo research to define clinical applications.
Authors
- Paolo Alberton (ORCID: https://orcid.org/0000-0001-6099-1051)
- Nikolaus Thierfelder (ORCID: https://orcid.org/0000-0003-1103-3775)
- Luisa Weber (ORCID: https://orcid.org/0009-0002-4800-6674)
- Benedikt Fuchs (ORCID: https://orcid.org/0000-0002-4539-6796)
- Riccardo E. Giunta (ORCID: https://orcid.org/0009-0007-7421-1213)
- Sinan Mert (ORCID: https://orcid.org/0009-0004-1244-5469)
- Maryam Hashemnia Sharbabaki
Institutions
- LMU Klinikum (DE)
- German Center for Lung Research (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Stem Cell Reviews and Reports
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1007/s12015-025-11002-7
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29