Metabolomics for searching non-invasive biomarkers of metabolic dysfunction-associated steatotic liver disease in youth with vertical HIV
Combining UDCA, TG54:5 and TG56:7 with the validated HSI score provides a potential model with high specificity and sensitivity for predicting MASLD in YWVH. Moreover, early alterations in the bile acid profile may help identify YWVH at risk of developing MASLD.
Authors
- Antonio Olveira (ORCID: https://orcid.org/0000-0002-2991-4688)
- Anna Rull (ORCID: https://orcid.org/0000-0002-8907-7754)
- Talía Sainz (ORCID: https://orcid.org/0000-0002-5301-0945)
- Marisa Montes (ORCID: https://orcid.org/0000-0003-1748-813X)
- Francesc Vidal (ORCID: https://orcid.org/0000-0002-6692-6186)
- Salvador Fernández‐Arroyo (ORCID: https://orcid.org/0000-0003-0147-1712)
- Sílvia Chafino (ORCID: https://orcid.org/0000-0001-9679-0622)
- Jara Hurtado‐Gallego (ORCID: https://orcid.org/0000-0003-2509-857X)
- Sonia Alcolea (ORCID: https://orcid.org/0000-0003-1233-1723)
- Consuelo Viladés (ORCID: https://orcid.org/0000-0002-2991-9593)
- Laura Tarancón‐Díez
- Marina Flores-Piñas (ORCID: https://orcid.org/0009-0001-4021-7701)
- Marı́a Luisa Navarro
- Joaquim Peraire
Institutions
- Universidad Complutense de Madrid (ES)
- Hospital Universitario La Paz (ES)
- Instituto de Salud Carlos III (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Institut de Recerca Biomèdica Catalunya Sud (ES)
- Hospital La Paz Institute for Health Research (ES)
- Centro de Investigación Biomédica en Red (ES)
- Centre for Omic Sciences (ES)
- Universitat Rovira i Virgili (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1038/s43856-025-01149-2
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Ministerio de Ciencia e Innovación
- Universitat Rovira i Virgili
- Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- Instituto de Salud Carlos III
- European Regional Development Fund