Maternal Socioeconomic Opportunity and Race‐Ethnicity Intersect to Influence Fetal Brain Volumes in Congenital Heart Disease
Results indicate that maternal COI likely modifies the relationship between maternal race-ethnicity and fetal brain development in CHD. The impact of maternal race-ethnicity and COI on brain development differs between fetuses with and without CHD. Addressing maternal social determinants of health could reduce disparities in neurodevelopmental outcomes in CHD. Although limitations in sample size temper conclusions, initial analysis suggests that maternal social determinants of health and environment can contribute to neurodevelopmental outcome variance in individuals with CHD.
Authors
- Jacqueline Weinberg (ORCID: https://orcid.org/0000-0002-1644-8649)
- Jodie K. Votava‐Smith (ORCID: https://orcid.org/0000-0002-8934-5333)
- Nhu Tran (ORCID: https://orcid.org/0000-0002-3429-6415)
- Rafael Ceschin (ORCID: https://orcid.org/0000-0002-3715-9627)
- William Reynolds (ORCID: https://orcid.org/0000-0002-7240-5213)
- Anthony Fabio (ORCID: https://orcid.org/0000-0002-6808-4939)
- Julia Wallace
- Vidya Rajagopalan (ORCID: https://orcid.org/0000-0002-7871-6768)
- Chunyan Wang (ORCID: https://orcid.org/0000-0002-0357-2907)
- Divya Patel (ORCID: https://orcid.org/0009-0003-3425-2978)
- Víctor G. Sal y Rosas
Institutions
- University of Southern California (US)
- Children's Hospital of Los Angeles (US)
- University of Pittsburgh (US)
- Children's Hospital of Pittsburgh (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1161/jaha.125.042029
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00