Targeted proteomics identifies differentially expressed proteins in Sjögren’s disease with incident lymphoma
We identified altered protein expression and an increased IFN system activation in SjD with incident lymphoma and pre-lymphoma. This knowledge may contribute to earlier detection of high-risk patients, identification of therapeutic targets and may ultimately improve SjD patient outcomes.
Authors
- Carin Backlin
- Cecilia Fugmann
- Juliana Imgenberg‐Kreuz (ORCID: https://orcid.org/0000-0002-7230-8990)
- Christopher Sjöwall (ORCID: https://orcid.org/0000-0003-0900-2048)
- Gunnel Nordmark (ORCID: https://orcid.org/0000-0002-3829-7431)
- E. Baecklund
- Anna-Maja Molin
- Anna Nikkarinen (ORCID: https://orcid.org/0009-0001-1451-0699)
- Alina Johansson
- Milica Vranic (ORCID: https://orcid.org/0000-0003-4412-7823)
- Per Eriksson (ORCID: https://orcid.org/0000-0002-3555-7162)
Institutions
- Linköping University (SE)
- Uppsala University (SE)
- Science for Life Laboratory (SE)
Publication Details
- Journal
- RMD Open
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1136/rmdopen-2025-005897
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Swedish Cancer Foundation
- Vetenskapsrådet
- Uppsala Universitet
- Agnes och Mac Rudbergs Stiftelse
- Reumatikerförbundet
- Science for Life Laboratory