Health-related quality of life in individuals with osteogenesis imperfecta in the United States: a cross-sectional study

These findings suggest that individuals with OI may not necessarily experience a greater mental health burden compared to the general population despite lower scores in areas of physical functioning. We speculate this discrepancy between mental and physical health scores may be partially explained by their increased resilience. Altogether, a comprehensive approach to care that recognizes all aspects of living with OI, including pain, social functioning, and daily activities, is needed when caring for individuals with OI.