A case of cutaneous vasculitis triggered by naproxen

Cutaneous vasculitis is an uncommon inflammatory condition affecting the small blood vessels of the skin. Although most cases are self-limiting, it is important that the condition is recognised and treated promptly, as progression can lead to systemic complications. This case study reports on the care of a 54-year-old man who developed bilateral lower-limb purpura a few weeks after starting naproxen for knee pain. Following assessment and investigations, naproxen was discontinued and oral prednisolone 40mg was prescribed. Within 2 weeks the lesions improved significantly, and the patient has remained well with no recurrence over more than a year of outpatient follow-up. This case highlights the need for vigilance when prescribing and monitoring patients on non-steroidal anti-inflammatory drugs. Nurses are central to recognising early skin changes, educating patients about potential adverse effects, and co-ordinating follow-up care. Effective communication and collaboration within the multidisciplinary team were crucial in achieving a positive outcome.