Association between low‐frequency oscillations in blood pressure variability and brain age derived from neuroimaging
Low-frequency oscillations in diastolic blood pressure variability, a marker of vasomotion, are reduced with aging. Low-frequency oscillations in diastolic blood pressure variability are favorably associated with BrainAGE gap, a marker of overall brain health, measured from neuroimaging. Reductions in vasomotion with aging may contribute to accelerated brain aging relative to chronological age.
Authors
- Richard P. Sloan (ORCID: https://orcid.org/0000-0003-4999-9209)
- Jill N. Barnes (ORCID: https://orcid.org/0000-0001-6317-4153)
- Derek C. Monroe (ORCID: https://orcid.org/0000-0003-3885-6878)
- Yaakov Stern (ORCID: https://orcid.org/0000-0002-2342-9497)
- Kevin S. Heffernan (ORCID: https://orcid.org/0000-0002-3499-1477)
- Stacey M. Schaefer (ORCID: https://orcid.org/0000-0003-4539-7219)
- Andrew S. London (ORCID: https://orcid.org/0000-0001-6339-4279)
Institutions
- University of North Carolina at Chapel Hill (US)
- University of Wisconsin–Madison (US)
- Columbia University Irving Medical Center (US)
- Neurobehavioral Systems (US)
- Syracuse University (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/alz.70833
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00