A Hybrid Convolutional Neural Network–Long Short-Term Memory (CNN–LSTM)–Attention Model Architecture for Precise Medical Image Analysis and Disease Diagnosis

<b>Background:</b> Deep learning (DL)-based medical image classification is becoming increasingly reliable, enabling physicians to make faster and more accurate decisions in diagnosis and treatment. A plethora of algorithms have been developed to classify and analyze various types of medical images. Among them, Convolutional Neural Networks (CNNs) have proven highly effective, particularly in medical image analysis and disease detection. <b>Methods:</b> To further enhance these capabilities, this research introduces MediVision, a hybrid DL-based model that integrates a vision backbone based on CNNs for feature extraction, capturing detailed patterns and structures essential for precise classification. These features are then processed through Long Short-Term Memory (LSTM), which identifies sequential dependencies to better recognize disease progression. An attention mechanism is then incorporated that selectively focuses on salient features detected by the LSTM, improving the model's ability to highlight critical abnormalities. Additionally, MediVision utilizes a skip connection, merging attention outputs with LSTM outputs along with Grad-CAM heatmap to visualize the most important regions of the analyzed medical image and further enhance feature representation and classification accuracy. <b>Results:</b> Tested on ten diverse medical image datasets (including, Alzheimer's disease, breast ultrasound, blood cell, chest X-ray, chest CT scans, diabetic retinopathy, kidney diseases, bone fracture multi-region, retinal OCT, and brain tumor), MediVision consistently achieved classification accuracies above 95%, with a peak of 98%. <b>Conclusions:</b> The proposed MediVision model offers a robust and effective framework for medical image classification, improving interpretability, reliability, and automated disease diagnosis. To support research reproducibility, the codes and datasets used in this study have been publicly made available through an open-access repository.

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Publication Details

Journal
Diagnostics
Published
2025-10-23
DOI
https://doi.org/10.3390/diagnostics15212673
Citations
3
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
7.44
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article

A Hybrid Convolutional Neural Network–Long Short-Term Memory (CNN–LSTM)–Attention Model Architecture for Precise Medical Image Analysis and Disease Diagnosis

Yazan M. Allawi, Salman Md Sultan, Hunseok Kang, Aymen I. Zreikat et al.
3 citations
Diagnostics
AI in cancer detection
7.44
article

A Hybrid Convolutional Neural Network–Long Short-Term Memory (CNN–LSTM)–Attention Model Architecture for Precise Medical Image Analysis and Disease Diagnosis

Yazan M. Allawi, Salman Md Sultan, Hunseok Kang, Aymen I. Zreikat, Wasan Alamro, Ahmad Abadleh, Md. Tanvir Hayat
article en
3 citations

Abstract

<b>Background:</b> Deep learning (DL)-based medical image classification is becoming increasingly reliable, enabling physicians to make faster and more accurate decisions in diagnosis and treatment. A plethora of algorithms have been developed to classify and analyze various types of medical images. Among them, Convolutional Neural Networks (CNNs) have proven highly effective, particularly in medical image analysis and disease detection. <b>Methods:</b> To further enhance these capabilities, this research introduces MediVision, a hybrid DL-based model that integrates a vision backbone based on CNNs for feature extraction, capturing detailed patterns and structures essential for precise classification. These features are then processed through Long Short-Term Memory (LSTM), which identifies sequential dependencies to better recognize disease progression. An attention mechanism is then incorporated that selectively focuses on salient features detected by the LSTM, improving the model's ability to highlight critical abnormalities. Additionally, MediVision utilizes a skip connection, merging attention outputs with LSTM outputs along with Grad-CAM heatmap to visualize the most important regions of the analyzed medical image and further enhance feature representation and classification accuracy. <b>Results:</b> Tested on ten diverse medical image datasets (including, Alzheimer's disease, breast ultrasound, blood cell, chest X-ray, chest CT scans, diabetic retinopathy, kidney diseases, bone fracture multi-region, retinal OCT, and brain tumor), MediVision consistently achieved classification accuracies above 95%, with a peak of 98%. <b>Conclusions:</b> The proposed MediVision model offers a robust and effective framework for medical image classification, improving interpretability, reliability, and automated disease diagnosis. To support research reproducibility, the codes and datasets used in this study have been publicly made available through an open-access repository.

DiagnosticsVol. 15(21)
Al-Ahliyya Amman University (JO), Princess Nourah bint Abdulrahman University (SA), Mutah University (JO), American University of the Middle East (KW), Innovative Research (United States) (US)
Openalex Percentile: Top 3%
AI in cancer detection
7.44
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