Anti-convulsant efficacy of long-acting injectable cannabidiol formulation (IVL5005) in the pentylenetetrazol-induced convulsions, with pharmacokinetic characterization

These results indicate that IVL5005 may overcome key limitations of oral CBD and support its further development as a long-acting therapeutic option for epilepsy.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-10-23
DOI
https://doi.org/10.3389/fphar.2025.1692123
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
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article

Anti-convulsant efficacy of long-acting injectable cannabidiol formulation (IVL5005) in the pentylenetetrazol-induced convulsions, with pharmacokinetic characterization

Slgirim Lee, Hyun‐Je Park, Young Dai Seo, Joo Young et al.
Frontiers in Pharmacology
Cannabis and Cannabinoid Research
article

Anti-convulsant efficacy of long-acting injectable cannabidiol formulation (IVL5005) in the pentylenetetrazol-induced convulsions, with pharmacokinetic characterization

Slgirim Lee, Hyun‐Je Park, Young Dai Seo, Joo Young, Woo‐Chan Son, So‐Young Youm, Kun Hee Park, Jae Ho Kim, Aeri Song
article en

Abstract

These results indicate that IVL5005 may overcome key limitations of oral CBD and support its further development as a long-acting therapeutic option for epilepsy.

Frontiers in PharmacologyVol. 16
Ulsan College (KR), Yuhan University (KR), Asan Medical Center (KR), University of Ulsan (KR), Korea Telecom (South Korea) (KR)
Openalex Percentile: Top 66%
Cannabis and Cannabinoid Research
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