HuoXue QianYang QuTan recipe attenuates myocardial hypertrophy in obese hypertensive rats by regulating MPC1/MCT4 mediated pyruvate-lactate metabolic axis
HQQR inhibits glycolysis and restores pyruvate-lactate metabolism in OBH rats by regulating MPC1/MCT4, thereby attenuating myocardial hypertrophy.
Authors
- Jing Wang (ORCID: https://orcid.org/0009-0009-5660-8799)
- Deyu Fu (ORCID: https://orcid.org/0000-0002-4678-8564)
- Da Li (ORCID: https://orcid.org/0000-0003-0629-0742)
- Jianhua Li (ORCID: https://orcid.org/0000-0001-7418-9465)
- Meng Wang (ORCID: https://orcid.org/0000-0001-7648-9955)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Huadong Hospital (CN)
- Yueyang Hospital (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1186/s13020-025-01240-9
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China