Teupolioside and Graminex (Xipag®) combined therapy induced anti-inflammatory effects and decreased dihydrotestosterone levels in the prostate tissue of patients with benign prostate hyperplasia: results of a pilot study
The short period of Xipag<sup>®</sup> administration effectively reduced DHT and PSA levels in patients affected by BPH. Additionally, it decreased CD4+ T lymphocyte infiltration while promoting CD8+ T lymphocytes, leading to a normalization of the prostate tissue inflammatory infiltrate.
Authors
- Francesco Bartoli (ORCID: https://orcid.org/0000-0002-2702-3259)
- Riccardo Giannini (ORCID: https://orcid.org/0000-0001-9740-0219)
- Alessandro Zucchi (ORCID: https://orcid.org/0000-0003-2252-4297)
- Pinuccia Faviana (ORCID: https://orcid.org/0000-0003-4283-1083)
- Matteo Pacini (ORCID: https://orcid.org/0009-0000-7293-1304)
- Petar Antonov (ORCID: https://orcid.org/0000-0003-4805-9178)
- Atanas Ivanov (ORCID: https://orcid.org/0000-0001-8831-3957)
- Riccardo Bartoletti (ORCID: https://orcid.org/0000-0002-0021-0302)
- Filippo Dazzi
- Rachele Volterrani
- Virginia D'Argliano
Institutions
- University of Pisa (IT)
- Medical University Plovdiv (BG)
Publication Details
- Journal
- Minerva Urology and Nephrology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.23736/s2724-6051.25.06446-8
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00