Effects of Dietary Sodium Modulation on Circulating Extracellular Vesicles
Dietary sodium modulates the expression of EV surface antigens associated with vascular inflammation, platelet activation, and endothelial function. Circulating EVs may mediate the effects of HS condition by interacting with endothelial cells, through multiple pathways, including RhoA activation and increased ICAM-1 expression.
Authors
- Paolo Mulatero (ORCID: https://orcid.org/0000-0002-5480-1116)
- Jacopo Burrello (ORCID: https://orcid.org/0000-0001-7884-7314)
- Brooke Honzel (ORCID: https://orcid.org/0009-0005-2824-903X)
- Martina Tetti
- Alessio Burrello (ORCID: https://orcid.org/0000-0002-6215-8220)
- Dario Di Silvestre (ORCID: https://orcid.org/0000-0002-7143-6229)
- Lucio Barile (ORCID: https://orcid.org/0000-0002-5827-0439)
- Stefania Bruno (ORCID: https://orcid.org/0000-0002-8879-9536)
- Silvia Monticone (ORCID: https://orcid.org/0000-0002-7322-2005)
- Anand Vaidya (ORCID: https://orcid.org/0000-0002-0314-9252)
- Fabrizio Buffolo (ORCID: https://orcid.org/0000-0001-9363-0199)
- Laura C Tsai (ORCID: https://orcid.org/0009-0008-5344-2589)
- Pierluigi Mauri (ORCID: https://orcid.org/0000-0001-9866-1816)
- Virginia Capuzzo
Institutions
- Brigham and Women's Hospital (US)
- Ente Ospedaliero Cantonale (CH)
- Epatocentro Ticino (CH)
- Department of Medical Sciences (BY)
- Institute of Biomedical Technologies (IT)
- University of Turin (IT)
- Università della Svizzera italiana (CH)
- University of Bologna (IT)
Publication Details
- Journal
- Hypertension
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25101
- Primary Topic
- Sodium Intake and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00