Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications

Laser-accelerated electron beams, in the so-called Very High-Energy Electron (VHEE) energy range, are of great interest for biomedical applications. For instance, laser-driven VHEE beams are envisaged to offer suitable compact accelerators for the promising field of FLASH radiotherapy. Radiobiology experiments carried out using laser-driven beams require the real-time knowledge of the dose delivered to the sample. We have developed an online dose monitoring procedure, using an Integrating Current Transformer (ICT) coupled to a suitable collimator, that allows the estimation of the delivered dose on a shot-to-shot basis under suitable assumptions. The cross-calibration of the measured charge with standard offline dosimetry measurements carried out with RadioChromic Films (RCFs) is discussed, demonstrating excellent correlation between the two measurements.

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Publication Details

Journal
Instruments
Published
2025-10-23
DOI
https://doi.org/10.3390/instruments9040025
Primary Topic
Nuclear Physics and Applications
Type
article
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article

Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications

P. Koester, Simona Piccinini, Lorenzo Fulgentini, F. Baffigi et al.
Instruments
Nuclear Physics and Applications
article

Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications

P. Koester, Simona Piccinini, Lorenzo Fulgentini, F. Baffigi, F. Brandi, Gabriele Bandini, Stephanie Vlachos, L. Labate, L. A. Gizzi, Daniele Palla, Federico Avella, M. Salvadori, David Gregocki
article en

Abstract

Laser-accelerated electron beams, in the so-called Very High-Energy Electron (VHEE) energy range, are of great interest for biomedical applications. For instance, laser-driven VHEE beams are envisaged to offer suitable compact accelerators for the promising field of FLASH radiotherapy. Radiobiology experiments carried out using laser-driven beams require the real-time knowledge of the dose delivered to the sample. We have developed an online dose monitoring procedure, using an Integrating Current Transformer (ICT) coupled to a suitable collimator, that allows the estimation of the delivered dose on a shot-to-shot basis under suitable assumptions. The cross-calibration of the measured charge with standard offline dosimetry measurements carried out with RadioChromic Films (RCFs) is discussed, demonstrating excellent correlation between the two measurements.

InstrumentsVol. 9(4)
University of Pisa (IT), Istituto di Scienza e Tecnologie dell'Informazione "Alessandro Faedo" (IT), Istituto Nazionale di Fisica Nucleare, Sezione di Pisa (IT)
Openalex Percentile: Top 60%
Nuclear Physics and Applications
DOIOpen Access PDFOpenAlex
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Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications — P. Koester, Simona Piccinini, et al. · Instruments (2025) | TGRS Research Map | TGRS