Respiratory infections in the post-COVID-19 era: impact, prevalence, and clinical characteristics of bacterial and viral co-infections
This study identified SARS-CoV-2, rhinoviruses, adenoviruses, and <i>Streptococcus pneumoniae</i> as key respiratory pathogens associated with mono- and co-infections. Mixed infections with SARS-CoV-2 were associated with progressively worsening symptoms, particularly in patients aged >65 years. This study highlights the need for preventive measures, including vaccination and revaccination of older adults with vaccines covering a broader range of <i>S. pneumoniae</i> serotypes.
Authors
- Neli Korsun (ORCID: https://orcid.org/0000-0002-3188-2283)
- Silvia Voleva
- Petar Velikov (ORCID: https://orcid.org/0000-0002-7436-4064)
- Svetla Angelova (ORCID: https://orcid.org/0000-0002-9119-6373)
- Victoria Levterova (ORCID: https://orcid.org/0000-0003-4975-4340)
- Ivan Ivanov (ORCID: https://orcid.org/0000-0002-2616-894X)
- Daniel Ivanov (ORCID: https://orcid.org/0009-0001-7360-4302)
- Iva Christova (ORCID: https://orcid.org/0000-0002-7878-3995)
- Daniela Pavlova (ORCID: https://orcid.org/0000-0001-8078-6776)
- Tatiana Tcherveniakova
- Ivelina Trifonova (ORCID: https://orcid.org/0000-0002-4543-6831)
- Ivan Simeonovski (ORCID: https://orcid.org/0000-0002-0182-3274)
- Maria Ivanova (ORCID: https://orcid.org/0000-0002-4343-7005)
- T. Dakov
Institutions
- Trakia University (BG)
- Medical University of Sofia (BG)
- University Hospital St. Ivan Rilski (BG)
- National Center of Infectious and Parasitic Diseases (BG)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-23
- DOI
- https://doi.org/10.3389/fmed.2025.1597782
- Citations
- 2
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Rice Research Institute, Indian Council of Agricultural Research