Retrospective analysis of the curative effect of Kanglaite injection on pancreatic cancer

Background: To systematically evaluate the curative effect of Kanglaite Injection (KLT) in treating pancreatic cancer (PC) by retrospective analysis. Methods: The clinical data of 172 patients with pancreatic cancer were analyzed, and the therapeutic effect, survival time and tumour markers of patients receiving Kanglaite injection combined with conventional chemotherapy were compared with those receiving conventional chemotherapy. Results: The univariate results showed that the two groups had WBC, LY#, MO#, NE#, ALB, FFA, CA199, CA125 in age, sex, tumour site, stage of pancreatic cancer, radiotherapy and metastasis, and laboratory indexes. Multivariate analysis showed that using KLT in pancreatic cancer patients was significantly related to gender and survival outcome, and KLT could prolong the survival of PC patients. In addition, the Chi-square test showed that patients with KLT could reduce the influence on monocyte count and albumin abnormality, which suggested that patients with KLT could reduce adverse reactions. Conclusions: Kanglaite injection combined with conventional radiotherapy and chemotherapy plays a significant role in improving therapeutic effect, immune function, and prolonging survival expression, and it will not increase the incidence of severe adverse reactions.

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Publication Details

Journal
Journal of Medical Biochemistry
Published
2025-10-23
DOI
https://doi.org/10.5937/jomb0-55284
Primary Topic
Microbial Metabolism and Applications
Type
article
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article

Retrospective analysis of the curative effect of Kanglaite injection on pancreatic cancer

Hongjuan Ji, Xian Miao, Jian Ruan, Dawei Qiao et al.
Journal of Medical Biochemistry
Microbial Metabolism and Applications
article

Retrospective analysis of the curative effect of Kanglaite injection on pancreatic cancer

Hongjuan Ji, Xian Miao, Jian Ruan, Dawei Qiao, Shuijie Shen, Shu Dong, Pei Cao, X. Y. Wen, Ling Zhang
article en

Abstract

Background: To systematically evaluate the curative effect of Kanglaite Injection (KLT) in treating pancreatic cancer (PC) by retrospective analysis. Methods: The clinical data of 172 patients with pancreatic cancer were analyzed, and the therapeutic effect, survival time and tumour markers of patients receiving Kanglaite injection combined with conventional chemotherapy were compared with those receiving conventional chemotherapy. Results: The univariate results showed that the two groups had WBC, LY#, MO#, NE#, ALB, FFA, CA199, CA125 in age, sex, tumour site, stage of pancreatic cancer, radiotherapy and metastasis, and laboratory indexes. Multivariate analysis showed that using KLT in pancreatic cancer patients was significantly related to gender and survival outcome, and KLT could prolong the survival of PC patients. In addition, the Chi-square test showed that patients with KLT could reduce the influence on monocyte count and albumin abnormality, which suggested that patients with KLT could reduce adverse reactions. Conclusions: Kanglaite injection combined with conventional radiotherapy and chemotherapy plays a significant role in improving therapeutic effect, immune function, and prolonging survival expression, and it will not increase the incidence of severe adverse reactions.

Journal of Medical BiochemistryVol. 45(2)
Guangzhou University of Chinese Medicine (CN), Nanjing University of Chinese Medicine (CN), Nantong University (CN), Affiliated Hospital of Nantong University (CN), Fudan University Shanghai Cancer Center (CN)
Openalex Percentile: Top 68%
Microbial Metabolism and Applications
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Retrospective analysis of the curative effect of Kanglaite injection on pancreatic cancer — Hongjuan Ji, Xian Miao, et al. · Journal of Medical Biochemistry (2025) | TGRS Research Map | TGRS