Plasma miRNAome Profiling Reveals Candidate Biomarkers for Low- and High-Dose Whole-Body Ionizing Radiation Exposure
This study identified distinct and shared circulating miRNA signatures for low- and high-dose radiation exposure. These findings support the potential of miRNAs as minimally invasive, dose-stratified biomarkers for radiation biodosimetry.
Authors
- Simon James Lees (ORCID: https://orcid.org/0000-0001-8892-4352)
- Christopher Thome (ORCID: https://orcid.org/0000-0002-0160-9657)
- Jessica Dougherty (ORCID: https://orcid.org/0000-0001-7065-0672)
- T.C. Tai (ORCID: https://orcid.org/0000-0001-7581-4234)
- Galicier Lionel
- Douglas R. Boreham (ORCID: https://orcid.org/0000-0001-7278-0171)
- Jocelyn S. Bel (ORCID: https://orcid.org/0000-0002-0683-4597)
- Ronan Derbowka
- Shayen Sreetharan
- Sujeenthar Tharmalingam (ORCID: https://orcid.org/0009-0007-0415-4831)
Institutions
- Health Sciences North (CA)
- Laurentian University (CA)
- Lakehead University (CA)
- NOSM University (CA)
- McMaster University (CA)
Publication Details
- Journal
- Dose-Response
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1177/15593258251391602
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00