Aggressive natural killer cell leukemia therapy in the L-asparaginase era: why are we failing?
HCT was associated with improved survival, particularly among patients who responded to initial therapy. However, given the high frequency of poor performance status at diagnosis, a stepwise approach, including early supportive care, careful chemotherapy administration, and timely HCT, is crucial for optimizing ANKL outcomes.
Authors
- Won Gu Kim (ORCID: https://orcid.org/0000-0002-8404-7759)
- Hyun-Young Kim (ORCID: https://orcid.org/0000-0001-8855-4988)
- Junhun Cho (ORCID: https://orcid.org/0000-0002-6089-9340)
- Sang Eun Yoon (ORCID: https://orcid.org/0000-0002-2472-8691)
- Seok Jin Kim
Institutions
- Samsung Medical Center (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Blood Research
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1007/s44313-025-00104-3
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea