Effect of gestational age on lymphocyte phenotypes in hospitalized preterm infants
This study provides a comprehensive characterization of adaptive immune development in hospitalized preterm infants during the first weeks of life, demonstrating a strong dependence on GA and modulation by perinatal factors. The identified distinct developmental profiles offer a valuable reference framework for interpreting immune phenotyping data and highlight potential associations between immunologic immaturity and clinical outcomes in this vulnerable population.
Authors
- Janina Marißen (ORCID: https://orcid.org/0000-0002-1779-3508)
- Wolfgang Göpel (ORCID: https://orcid.org/0000-0002-6486-4727)
- Dorothee Viemann (ORCID: https://orcid.org/0000-0002-9009-3559)
- Sofia Kirke Forslund (ORCID: https://orcid.org/0000-0003-4285-6993)
- Julia Pagel (ORCID: https://orcid.org/0000-0002-8427-0213)
- Marie-Theres Dammann (ORCID: https://orcid.org/0000-0002-3731-8456)
- Johannes Dirks (ORCID: https://orcid.org/0000-0002-1244-6670)
- Mats Ingmar Fortmann (ORCID: https://orcid.org/0000-0003-1676-8340)
- K. Dahm (ORCID: https://orcid.org/0000-0002-6819-2622)
- Jan Rupp (ORCID: https://orcid.org/0000-0001-8722-1233)
- Christoph Härtel (ORCID: https://orcid.org/0000-0002-2181-7322)
- Henner Morbach
- Till Birkner (ORCID: https://orcid.org/0000-0003-2656-2821)
- Lilith Reichert
- Henry Kipke
Institutions
- Universität Hamburg (DE)
- Max Delbrück Center (DE)
- German Center for Neurodegenerative Diseases (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- University Hospital Schleswig-Holstein (DE)
- German Center for Infection Research (DE)
- Universitätsklinikum Würzburg (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1016/j.jaci.2025.09.030
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00