Immunoinformatics and molecular docking reveal potential multi-epitope vaccine against <i>Pseudomonas aeruginosa</i>
The selected epitopes showed strong potential for inclusion in a peptide-based PaMEV, with favorable immunogenicity and docking results supporting its design. The final construct exhibited structural stability and strong HLA interactions, suggesting it as a promising vaccine candidate against <i>P. aeruginosa</i>. Experimental validation through <i>in vitro</i> and <i>in vivo</i> studies is recommended.
Authors
- A. So
- Alberto Geronimo
- Edward Kevin B. Bragais (ORCID: https://orcid.org/0000-0002-8470-3111)
- Derreck O. De Leon
- Ma. Vianca Julia E. Anupol
- Keona Tiffany B. Prieto
- Mellissa Jewel S. Magday
Institutions
- Ateneo de Manila University (PH)
- University of the Philippines Manila (PH)
Publication Details
- Journal
- Clinical and Experimental Vaccine Research
- Published
- 2025-10-23
- DOI
- https://doi.org/10.7774/cevr.2026.15.e2
- Primary Topic
- vaccines and immunoinformatics approaches
- Type
- article
- Field-Weighted Citation Impact
- 0.00