Development and validation of a novel signature to predict the survival and affect the immune microenvironment of esophageal squamous cell carcinoma: epigenetic-related genes
The findings of this study offer clinically relevant insights for prognostic stratification and characterization of the immune microenvironment in ESCC patients. Moreover, these results provide novel perspectives that may contribute to the development of more effective prognostic tools and targeted therapeutic strategies for ESCC management.
Authors
- Yani Su (ORCID: https://orcid.org/0000-0003-2969-4045)
- Xianjie Wan
- Pengfei Wen (ORCID: https://orcid.org/0000-0001-8873-5172)
- Jiale Xie (ORCID: https://orcid.org/0000-0002-9967-4966)
- Mingyi Yang (ORCID: https://orcid.org/0000-0001-8640-9795)
- Zhi Yang (ORCID: https://orcid.org/0000-0001-6636-4606)
- Lin Liu (ORCID: https://orcid.org/0000-0003-4748-8755)
- Peng Xu (ORCID: https://orcid.org/0000-0002-7573-4813)
- Qiong Zhang (ORCID: https://orcid.org/0000-0002-5360-3951)
- Ming Zhang (ORCID: https://orcid.org/0000-0003-0794-2546)
- Ke Xu (ORCID: https://orcid.org/0000-0002-7689-750X)
Institutions
- Xi'an Honghui Hospital (CN)
- Tang Du Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.3389/fimmu.2025.1670600
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00