Electroacupuncture improves scopolamine hydrobromide induced dry eye in mice via inhibiting ocular surface inflammation and regulating the HMGB1-related signaling pathways
The findings presented in our study demonstrate that EA may improve ocular surface inflammation in mice with DED by inhibiting the HMGB1-related signaling pathways. Therefore, EA may be a potential therapeutic target for DED.
Authors
- Shangjie Liang
- Yutong Han (ORCID: https://orcid.org/0000-0003-3323-6426)
- Siyuan Fan (ORCID: https://orcid.org/0000-0001-8016-9110)
- Qingbo Wei (ORCID: https://orcid.org/0000-0002-3577-5661)
- Yunchuan Wu (ORCID: https://orcid.org/0000-0002-7059-9229)
- Ning Ding (ORCID: https://orcid.org/0000-0003-2259-9053)
- Xia Wu (ORCID: https://orcid.org/0000-0002-8237-3315)
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-23
- DOI
- https://doi.org/10.3389/fmed.2025.1664376
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Jiangsu Provincial Department of Education
- Nanjing University of Chinese Medicine
- Nanjing University