A novel multi-epitope mRNA vaccine against colorectal cancer: in silico design and immune efficacy profiling

This study presents an in silico designed mRNA vaccine against colorectal cancer (CRC). Immune simulations demonstrated that this mRNA vaccine can elicit strong antitumor immune responses, indicating it is an effective and promising candidate that warrants further <i>in vitro</i> and <i>in vivo</i> investigations. Additionally, this work highlights the potential of in silico approaches in vaccine design and provides valuable insights for the development of effective vaccines targeting CRC.