Elevated KNSTRN as a potential indicator for triple-negative breast cancer progression and immune infiltration

KNSTRN is a candidate biomarker for TNBC prognosis and a potential target for immunotherapeutic strategies. Its overexpression in TNBC is associated with aggressive tumor behavior and an immunosuppressive microenvironment, highlighting its significance in TNBC pathogenesis and prognosis.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-10-23
DOI
https://doi.org/10.3389/fimmu.2025.1572359
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Elevated KNSTRN as a potential indicator for triple-negative breast cancer progression and immune infiltration

Minfang Qi, Yuan Cao, Xiao Liu, Zhijia Sun et al.
Frontiers in Immunology
Ferroptosis and cancer prognosis
article

Elevated KNSTRN as a potential indicator for triple-negative breast cancer progression and immune infiltration

Minfang Qi, Yuan Cao, Xiao Liu, Zhijia Sun, Yurong Song, Yuxi Liu
article en

Abstract

KNSTRN is a candidate biomarker for TNBC prognosis and a potential target for immunotherapeutic strategies. Its overexpression in TNBC is associated with aggressive tumor behavior and an immunosuppressive microenvironment, highlighting its significance in TNBC pathogenesis and prognosis.

Frontiers in ImmunologyVol. 16
Guilin Medical University (CN), 82th Hospital of Pla (CN)
Openalex Percentile: Top 57%
Ferroptosis and cancer prognosis
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