Global burden and trends of Klebsiella pneumoniae infection, 1990–2021: insights from the global burden of disease study

Over the past 32 years, the global burden of <i>KP</i> infection in the lower respiratory tract has generally declined, but it has increased among the older population in Central/Eastern Europe and Central Asia. This rise is likely due to inappropriate antibiotic use, widespread antimicrobial resistance, emerging virulent and multidrug-resistant strains, and an aging population, highlighting the need for vigilant monitoring and intervention measures.