Impact of dexmedetomidine on postoperative cognitive dysfunction and inflammatory response in older adult female patients undergoing laparoscopic cholecystectomy
In conclusion, compared with normal saline, a 0.6 μg/kg/h maintenance dose of Dex is the optimal dosing regimen for improving postoperative cognitive function and had a better anti-inflammation effect in elderly female patients following LC.
Authors
- Yanlong Fu
- Qingtao Zhao (ORCID: https://orcid.org/0000-0001-6400-2329)
- Xiaoli Dong
- Zhenliang Wang
- Qiang Wei (ORCID: https://orcid.org/0000-0003-3750-3042)
- Wenxin Shi
Institutions
- Fujian Medical University (CN)
- North China University of Science and Technology (CN)
- Hospital of Hebei Province (CN)
- Hebei General Hospital (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Surgery
- Published
- 2025-10-23
- DOI
- https://doi.org/10.3389/fsurg.2025.1636040
- Citations
- 1
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.55