Oxidative low-density lipoprotein and shear induced calcification within a calcific aortic valve disease-on-a-chip platform
Given that CAVD has no targeted intervention, continued evolution of this CAVD-on-a-chip model sheds light on mechanisms in disease onset and can lead to significant contributions in preclinical drug development.
Authors
- Gretchen J. Mahler (ORCID: https://orcid.org/0000-0002-7286-8920)
- Peter Huang (ORCID: https://orcid.org/0000-0002-5547-5906)
- Mei‐Hsiu Chen (ORCID: https://orcid.org/0000-0003-0566-073X)
- Melissa Mendoza-Seale
Institutions
- Binghamton University (US)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-10-23
- DOI
- https://doi.org/10.3389/fcvm.2025.1655341
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health Sciences Centre Foundation
- Binghamton University