Necrotizing myometritis following vaginal delivery complicated by retained placenta and uterine artery embolization: A case report

Necrotizing myometritis (NM) is a rare but life-threatening postpartum infection. Although most reported cases are attributed to <i>Group A Streptococcus</i> (GAS), NM can also arise as a polymicrobial process in the setting of uterine ischemia, particularly after uterine artery embolization (UAE), and this phenotype often follows a slower, more insidious course that may require different diagnostic and therapeutic strategies. We describe NM due to <i>Enterococcus faecium</i>, <i>Klebsiella pneumoniae</i>, and <i>Eggerthella lenta</i> after retained placenta and UAE. In contrast to the fulminant trajectory typical of GAS-associated NM, this case evolved over 48 days with intermittent symptom remission and ultimately required hysterectomy despite multiple courses of antibiotics and repeated curettage. This case highlights the need to broaden empiric antibiotics to include coverage for anaerobes and enterococci, which are frequently resistant to standard postpartum regimens, and indicates that sonographic findings such as myometrial heterogeneity, hypoperfusion, and tissue discontinuity may provide earlier diagnostic clues than clinical signs alone and should prompt early MRI evaluation. Early recognition of these atypical features is critical to avoid diagnostic delay and improve maternal outcomes.

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Publication Details

Journal
SAGE Open Medical Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1177/2050313x251388740
Primary Topic
Maternal and fetal healthcare
Type
article
Field-Weighted Citation Impact
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article

Necrotizing myometritis following vaginal delivery complicated by retained placenta and uterine artery embolization: A case report

Jianlin Cao, Linxiao Fan, Yifei Fan, Y. Zhang et al.
SAGE Open Medical Case Reports
Maternal and fetal healthcare
article

Necrotizing myometritis following vaginal delivery complicated by retained placenta and uterine artery embolization: A case report

Jianlin Cao, Linxiao Fan, Yifei Fan, Y. Zhang, Guoxia Guo
article en

Abstract

Necrotizing myometritis (NM) is a rare but life-threatening postpartum infection. Although most reported cases are attributed to <i>Group A Streptococcus</i> (GAS), NM can also arise as a polymicrobial process in the setting of uterine ischemia, particularly after uterine artery embolization (UAE), and this phenotype often follows a slower, more insidious course that may require different diagnostic and therapeutic strategies. We describe NM due to <i>Enterococcus faecium</i>, <i>Klebsiella pneumoniae</i>, and <i>Eggerthella lenta</i> after retained placenta and UAE. In contrast to the fulminant trajectory typical of GAS-associated NM, this case evolved over 48 days with intermittent symptom remission and ultimately required hysterectomy despite multiple courses of antibiotics and repeated curettage. This case highlights the need to broaden empiric antibiotics to include coverage for anaerobes and enterococci, which are frequently resistant to standard postpartum regimens, and indicates that sonographic findings such as myometrial heterogeneity, hypoperfusion, and tissue discontinuity may provide earlier diagnostic clues than clinical signs alone and should prompt early MRI evaluation. Early recognition of these atypical features is critical to avoid diagnostic delay and improve maternal outcomes.

SAGE Open Medical Case ReportsVol. 13
Shanxi Medical University (CN)
Openalex Percentile: Top 57%
Maternal and fetal healthcare
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