Effect of ayres sensory integration ®-based occupational therapy intervention on sensory processing in a child with 4p trisomy and 10q monosomy: a case report

This study examined the effects of Ayres Sensory Integration ® (ASI) -based occupational therapy intervention on sensory processing in a 12-month-old boy with Trisomy 4p and Monosomy 10q. Sensory processing was assessed using the Test of Sensory Functions in Infants (TSFI) before and after a 24-week intervention consisting of twice-weekly, 45-minute individualized ASI ® sessions conducted by a certified occupational therapist. Increases in raw scores were observed across all TSFI subdomains and the total score. Improvements were observed in raw scores across all TSFI subdomains and in the total score. Notably, visual-tactile integration and oculomotor control showed measurable improvement, shifting from the “abnormal” to the “at-risk” range. However, other subdomains remained within the “abnormal” classification, and the overall TSFI classification continued to indicate sensory processing difficulties. Although positive changes were observed in the child’s responses and abilities following the intervention, the severity of his sensory processing challenges indicates a need for ongoing long-term therapeutic support.