Transcatheter valve implantation for aortic stenosis: acronym matters
In 2002, Alain Cribier performed the first transcatheter aortic valve implantation (TAVI).Since then, TAVI has evolved from an experimental procedure into a consolidated and globally widespread therapeutic strategy.To date, nearly 3 million patients in more than 80 countries have undergone TAVI, and its use is increasingly surpassing that of surgical aortic valve replacement (SAVR).The new 2025 ESC/EACTS Guidelines for the Management of Valvular Heart Disease are expected to further expand TAVI indications.Specifically, the updated guidelines introduce a new age threshold of 70 years for TAVI (Class I, Level A).Moreover, intervention should be considered in asymptomatic patients with severe, high-gradient aortic stenosis and preserved left ventricular ejection fraction (LVEF 50%), as an alternative to close active surveillance, provided the procedural risk is low (Class IIa, Level A).
Authors
- Ciro Indolfi (ORCID: https://orcid.org/0000-0003-1241-6487)
- Carmen Spaccarotella (ORCID: https://orcid.org/0000-0003-1825-0510)
- Giovanni Esposito (ORCID: https://orcid.org/0000-0003-0565-7127)
- Thomas F. Lüscher
Institutions
- University of Zurich (CH)
- Harefield Hospital (GB)
- European Society of Cardiology (FR)
- Royal Brompton Hospital (GB)
- University Hospital of Zurich (CH)
- Lung Institute (US)
- Center for Pediatric Endocrinology Zurich (CH)
- University College London (GB)
- University of Calabria (IT)
- Imperial College London (GB)
- University of Naples Federico II (IT)
Publication Details
- Journal
- European Heart Journal - Valvular and Structural Heart Disease
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1093/ehjvshd/xwaf003
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00