Transcatheter valve implantation for aortic stenosis: acronym matters

In 2002, Alain Cribier performed the first transcatheter aortic valve implantation (TAVI).Since then, TAVI has evolved from an experimental procedure into a consolidated and globally widespread therapeutic strategy.To date, nearly 3 million patients in more than 80 countries have undergone TAVI, and its use is increasingly surpassing that of surgical aortic valve replacement (SAVR).The new 2025 ESC/EACTS Guidelines for the Management of Valvular Heart Disease are expected to further expand TAVI indications.Specifically, the updated guidelines introduce a new age threshold of 70 years for TAVI (Class I, Level A).Moreover, intervention should be considered in asymptomatic patients with severe, high-gradient aortic stenosis and preserved left ventricular ejection fraction (LVEF 50%), as an alternative to close active surveillance, provided the procedural risk is low (Class IIa, Level A).

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Publication Details

Journal
European Heart Journal - Valvular and Structural Heart Disease
Published
2025-10-01
DOI
https://doi.org/10.1093/ehjvshd/xwaf003
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Transcatheter valve implantation for aortic stenosis: acronym matters

Ciro Indolfi, Carmen Spaccarotella, Giovanni Esposito, Thomas F. Lüscher
European Heart Journal - Valvular and Structural Heart Disease
Cardiac Valve Diseases and Treatments
article

Transcatheter valve implantation for aortic stenosis: acronym matters

Ciro Indolfi, Carmen Spaccarotella, Giovanni Esposito, Thomas F. Lüscher
article en

Abstract

In 2002, Alain Cribier performed the first transcatheter aortic valve implantation (TAVI).Since then, TAVI has evolved from an experimental procedure into a consolidated and globally widespread therapeutic strategy.To date, nearly 3 million patients in more than 80 countries have undergone TAVI, and its use is increasingly surpassing that of surgical aortic valve replacement (SAVR).The new 2025 ESC/EACTS Guidelines for the Management of Valvular Heart Disease are expected to further expand TAVI indications.Specifically, the updated guidelines introduce a new age threshold of 70 years for TAVI (Class I, Level A).Moreover, intervention should be considered in asymptomatic patients with severe, high-gradient aortic stenosis and preserved left ventricular ejection fraction (LVEF 50%), as an alternative to close active surveillance, provided the procedural risk is low (Class IIa, Level A).

European Heart Journal - Valvular and Structural Heart DiseaseVol. 1(1)
University of Zurich (CH), Harefield Hospital (GB), European Society of Cardiology (FR), Royal Brompton Hospital (GB), University Hospital of Zurich (CH), Lung Institute (US), Center for Pediatric Endocrinology Zurich (CH), University College London (GB), University of Calabria (IT), Imperial College London (GB), University of Naples Federico II (IT)
Openalex Percentile: Top 54%
Cardiac Valve Diseases and Treatments
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Transcatheter valve implantation for aortic stenosis: acronym matters — Ciro Indolfi, Carmen Spaccarotella, et al. · European Heart Journal - Valvular and Structural Heart Disease (2025) | TGRS Research Map | TGRS