Lipidomic Profiling Reveals Phenotype‐Specific Metabolic Signatures in Obese and Hyperuricemic Children
Lipid metabolism displays phenotype-specific regulatory patterns across distinct clinical presentations, with differential pathway involvement and functional enrichment. Key lipid species such as TG, PC, and Cer may serve as potential subtype biomarkers or therapeutic targets, offering novel insights into the early identification and precision management of metabolic disturbances in children.
Authors
- Jin Cai (ORCID: https://orcid.org/0000-0003-1597-8143)
- Yuhang Wang (ORCID: https://orcid.org/0009-0002-0167-419X)
- Shuang Shi (ORCID: https://orcid.org/0000-0002-8134-0300)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Zhumadian Central Hospital (CN)
- Maternity and Children's Hospital (SA)
- Yiwu Science and Technology Research Institute (CN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1002/rcm.10157
- Citations
- 1
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.81