Effectiveness and Safety of Acupuncture with Acupoint-to-Acupoint Penetrating Needling Technique for Post-Stroke Dysphagia: A Systematic Review and Meta-Analysis

Background: Post-stroke dysphagia (PSD) is a common complication that increases the risk of aspiration pneumonia, malnutrition, and mortality. Acupoint-to-acupoint penetrating needling (AAPN) technique is a potential therapeutic option, but its efficacy and safety remain unclear. This study systematically evaluated acupuncture combined with AAPN for PSD through a meta-analysis of randomized controlled trials (RCTs).Methods: Seven databases were searched up to July 14, 2025. Data were synthesized using a random-effects model, and study quality was assessed with the Cochrane RoB 2.0 tool.Results: Ten RCTs involving 625 participants were included. Compared to swallowing rehabilitation and conventional acupuncture, acupuncture combined with AAPN significantly improved swallowing function. Adverse events were more frequent than with swallowing rehabilitation but were mild, with no serious events; safety was comparable to conventional acupuncture.Conclusions: Acupuncture with AAPN shows promising efficacy and a favorable safety profile for PSD. Further high-quality trials are warranted.