Clinical and pathological characteristics of CRS with nasal polyps in patients with asthma–COPD overlap

CRS-ACO patients were prone to recurrence of nasal polyps, and the pathology of nasal polyps in CRS-ACO patients were significantly infiltrated with neutrophilic inflammatory cells. CRS-ACO patients revealed inflammatory cell infiltration in the upper airway (nasal polyps) and similar cell types was confirmed to coexist in the lower airway, suggests the possibility of a "one airway, one disease" concept, not only in BA, but also in ACO as well.