<i>Mycoplasma pneumoniae</i> ‐Associated Mucositis: A Diagnostic Dilemma

Fuchs syndrome is a mucosal variant of Stevens-Johnson syndrome (SJS) without cutaneous lesions, mostly affecting the mucosa of the mouth, conjunctiva, and genitalia, that occurs in a background of <i>Mycoplasma pneumoniae</i> and herpes simplex infection. Treatment with antibiotics such as macrolides, tetracycline, or fluoroquinolones has been shown to limit the pulmonary disease, but it is unclear whether the incidence or severity of the mucocutaneous eruption is reduced. In the absence of cutaneous manifestations, the patient often seeks multiple specialists, including ophthalmologists, dentists, otolaryngologists, gynecologists, or urologists, so a suspicion of <i>Mycoplasma</i> in such cases can avoid delay in diagnosis and adverse sequelae. We hereby report a case of <i>Mycoplasma pneumoniae</i>-associated Fuchs syndrome which showed significant improvement with oral antibiotics.

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Publication Details

Journal
Clinical Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1002/ccr3.71338
Primary Topic
Pneumonia and Respiratory Infections
Type
article
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article

Mycoplasma pneumoniae ‐Associated Mucositis: A Diagnostic Dilemma

Sagar Maharjan, Sabita Paudel, M Mathur, Sandhya Regmi et al.
Clinical Case Reports
Pneumonia and Respiratory Infections
article

Mycoplasma pneumoniae ‐Associated Mucositis: A Diagnostic Dilemma

Sagar Maharjan, Sabita Paudel, M Mathur, Sandhya Regmi, Sambidha Karki, Nabita Bhattarai
article en

Abstract

Fuchs syndrome is a mucosal variant of Stevens-Johnson syndrome (SJS) without cutaneous lesions, mostly affecting the mucosa of the mouth, conjunctiva, and genitalia, that occurs in a background of <i>Mycoplasma pneumoniae</i> and herpes simplex infection. Treatment with antibiotics such as macrolides, tetracycline, or fluoroquinolones has been shown to limit the pulmonary disease, but it is unclear whether the incidence or severity of the mucocutaneous eruption is reduced. In the absence of cutaneous manifestations, the patient often seeks multiple specialists, including ophthalmologists, dentists, otolaryngologists, gynecologists, or urologists, so a suspicion of <i>Mycoplasma</i> in such cases can avoid delay in diagnosis and adverse sequelae. We hereby report a case of <i>Mycoplasma pneumoniae</i>-associated Fuchs syndrome which showed significant improvement with oral antibiotics.

Clinical Case ReportsVol. 13(10)
College of Medical Sciences (NP)
Openalex Percentile: Top 59%
Pneumonia and Respiratory Infections
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