Impact of Increasing Referral for 99mTc-DPD Scintigraphy on Prognosis Across the Phenotypic Spectrum of Restrictive Cardiomyopathy
There is strikingly high mortality among patients with negative <sup>99m</sup>Tc-DPD scintigraphy, equivalent to that of ATTR-CM. This finding serves as a call for future studies to better characterise this seemingly overlooked cohort, with the aim of developing targeted therapies and improving outcomes.
Authors
- Khalid Hussain (ORCID: https://orcid.org/0000-0002-3714-8696)
- Kenneth Parker
- Lauren Turvey-Haigh
- Shanat Baig (ORCID: https://orcid.org/0000-0003-1625-6839)
- William Bradlow (ORCID: https://orcid.org/0000-0001-9766-5321)
- Richard P. Steeds (ORCID: https://orcid.org/0000-0001-5687-2535)
- Chun Shing Kwok (ORCID: https://orcid.org/0000-0001-7047-1586)
- Julian D. Gillmore (ORCID: https://orcid.org/0000-0001-6174-9232)
- Yasmin Wahid
- Jennifer H. Pinney (ORCID: https://orcid.org/0000-0001-8718-8066)
- William E. Moody (ORCID: https://orcid.org/0000-0002-2592-618X)
- James Cullis
- Chern Hsiang Choy
- Boyang Liu (ORCID: https://orcid.org/0000-0002-3497-6867)
- P Parekh (ORCID: https://orcid.org/0000-0002-0250-0434)
- A Akhtar
- Alex Zaphiriou
Institutions
- University Hospitals Birmingham NHS Foundation Trust (GB)
- The Royal Free Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- JACC Advances
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1016/j.jacadv.2025.102230
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00