SUN-570 Mobile Application for Self-Management of Type 2 Diabetes Mellitus: Randomized Controlled Trial

Abstract Disclosure: S. Wongdama: None. W. Paemueang: None. C. Sriphrapradang: None. Background: Mobile apps have emerged as tools to support improved glycemic control, primarily focusing on diabetes self-management. However, existing proven apps have not yet been tailored to the lifestyle of Thai individuals. The Rama Diabetes Care application was developed to provide comprehensive diabetes management and include information on Thai cuisine. Objective: To evaluate the effectiveness of the Rama Diabetes Care application in improving blood glucose control and self-care behaviors among outpatients with uncontrolled type 2 diabetes at Ramathibodi hospital. Methods: A randomized controlled trial was conducted among patients with type 2 diabetes who had smartphone access and a HbA1c level >7% within the past three months. Participants were randomized into either the intervention group (using the mobile application) or the control group (receiving standard care). All patients participated in a Diabetes Self-Management Education and Support (DSMES) program. The intervention group received additional training on using the app, which they were encouraged to use daily. Outcomes were assessed at 3 and 6 months. The primary outcome was HbA1c, while secondary outcomes included LDL-c, eGFR, body mass index, self-care behaviors, and patient satisfaction (assessed via a Likert scale). Results: A total of 129 patients participated, with 64 in the intervention group and 65 in the control group. The mean age in the intervention group was 54.6±14.31 years, which was significantly different from 61.9±11.98 years in the control group (p=0.002). The mean baseline HbA1c level in the intervention group was 9.2±1.96 %, similar to the control group. While a greater reduction of HbA1c was observed in the intervention group, no significant difference was found between groups (p=0.13). However, in patients under 65 years, the intervention group had significantly lower fasting plasma glucose at 6 months (mean difference -29.3 mg/dL; 95%CI, -55.29, -3.31, p=0.027). The satisfaction score for the apps in the intervention group was 24.2 out of 35. Conclusions: The app demonstrated similar glycemic control compared to standard care, but showed a significant reduction in fasting plasma glucose levels among individuals under 65. Tailoring diabetes self-management interventions to meet individual needs in type 2 diabetes is essential(National Clinical Trials Registry, NCT06176703) Presentation: Sunday, July 13, 2025