SUN-569 The Efficacy of Mobile Application on Diabetes Prevention Compared with Standard of Care in Adults with Prediabetes: Randomized Controlled Trial

Abstract Disclosure: N. Wonghakaeo: None. Aims: To investigate the efficacy of a mobile application compared with a control group receiving standard care in prediabetic patients. Methods: Healthcare personnel at King Chulalongkorn Memorial Hospital with prediabetes (N=131) were randomized into either the mobile application group or the standard care group. The primary outcome was the change in fasting plasma glucose (FPG) at 6 months. The secondary outcomes were changes in anthropometric, metabolic parameters, and quality of life. Results: The changes in bodyweight, waist circumference, and HbA1C between groups were significantly different at 6 months between the groups, but there is no difference in FPG (mean difference -2.60 mg/dL [95% CI -5.73, 0.52], p=0.102). At 6 months, 11 participants (17.2%) in the application group reversed to normoglycemia, compared to, 4 participants (6%) in the standard care group. Conclusion: Mobile applications is an innovative and effective way to improve health outcomes by reducing body weight, waist circumference, HbA1c at 6 months, increasing muscle mass at 6 months, and increasing a rate of transition from prediabetes to normoglycemia than standard care. Presentation: Sunday, July 13, 2025