SUN-146 Characterization of Children and Adolescents With Gender Dysphoria at a Reference Centre in Bogota, Colombia

Abstract Disclosure: D. ramirez: None. V. Leal: None. W. Morales: None. S. Awadalla: None. Introduction: Due to the increased demand for the management of gender dysphoria (GD) in childhood in Colombia, there is a need for data on the general characteristics of these transgender youth. The objective was to characterize the population of children and adolescents referred to the specialized Gender Identity Centre at San José Hospital in Bogotá between January 2014 and January 2024.Method: a retrospective cohort study of children and adolescents with GD. Data were expressed as means ± standard deviation (SD).Results: 56 children were included, a higher number of transmasculine youths were observed, with 33 (58.9%, assigned female at birth with male gender identity) and 23 transfeminine youths (41.1%). The mean age of onset for gender incongruence was 8 ± 3.8 years, with 69.6% reporting distress and 30.4% displaying opposite-sex behaviors. The mean age of social transition, characterized by appearance changes, was 14 ± 2.7 years, with name change at 14.5 ± 6 years. The mean age of GD confirmation by psychiatry was 16 ± 1.6 years. Only 23 patients (41%) received GnRH analogue therapy, with a median age of 15 ± 1.2 years; 5 patients for 3 years, 1 patient for 4 years, 8 patients for 1 year, and 1 patient for 3 years. No adverse effects were reported. Among those receiving GnRH therapy, the majority were transmasculine n=15 (65.2%), while 8 (34.7%) were transfeminine.Cross-sex hormone therapy (CSHT) was initiated in 39 (69.9%) patients, with the majority starting at 18 years (45%) and 35% starting at 17 years, with no reported adverse effects. Depression was reported in 19.6% of patients, while anxiety and/or suicide attempts were observed in less than 3.6% of cases.Conclusion: The diagnostic workout and medical treatment for children and adolescents referred for gender dysphoria vary widely. It is essential that these protocols align with international guidelines and consensus to ensure the highest standard of care Presentation: Sunday, July 13, 2025