MON-248 Trends In Obesity Related Co Morbidities In Adolescents :insights From Western India

Abstract Disclosure: P.H. Phatale: None. S.H. Phatale: None. H. Phatale: None. Background: Adolescent obesity is a growing public health concern linked to early-onset comorbidities that extend into adulthood, increasing the lifelong risk of non-communicable diseases. Clinic-based data provide vital insights into the prevalence and pattern of comorbidities in this high-risk group.Objective:To assess the prevalence and pattern of comorbidities among adolescents with obesity in a clinical setting.Methods:This retrospective study evaluated medical records of adolescents (10–19 years) diagnosed with overweight or obesity who attended Samrat Endocrine Institute between October 2023 and April 2025. Categorization into overweight and obese groups was based on Revised IAP Growth Charts. Data collected included demographics, clinical assessments, and laboratory results. Comorbidities assessed were prediabetes, diabetes mellitus (DM), elevated blood pressure (BP), hypertension (HT), dyslipidemia, insulin resistance (IR), delayed puberty, chronic anovulatory cycles, and hyperandrogenism. Descriptive statistics determined prevalence; chi-square tests assessed associations between BMI category and comorbidities. Results:Records of 210 adolescents (mean age 13.7 ± 2.47 years; M:F = 1.2:1) were reviewed, including 177 (84.2%) obese and 33 (15.7%) overweight individuals. Central obesity was observed in 169 (80.4%). Based on HbA1c, 154 (73.3%) had normal levels, 54 (25.7%) were prediabetic and 2 (0.95%) were diabetic. Among <13 years: 68.4% were normotensive, 12.7% had elevated BP, and 19.0% were hypertensive. Among ≥13 years: 51.1% were normotensive, 34.4% had elevated BP, and 14.5% were hypertensive. Dyslipidemia (low HDL, high triglycerides) was seen in 56 (26.7%). IR was present in 29.5% of girls and 24.3% of boys. Delayed puberty was noted in 13.9% of boys. Among girls, 48.4% had chronic anovulatory cycles and 27.4% had hyperandrogenism. Statistically significant difference was found only for delayed puberty in boys (p=0.05).Conclusion:High rates of comorbidities in both obese and overweight adolescents underscore the need for systematic screening and early intervention. The higher prevalence of IR and reproductive issues in girls warrants focused attention to mitigate long-term metabolic consequences. Keywords: Adolescent obesity, Comorbidities, Dyslipidemia, Hypertension, Insulin resistance, Prediabetes, DM, Hyperandrogenism, IAP(Indian Academy Of Pediatrics) Presentation: Monday, July 14, 2025