Green-Synthesized Silver Nanoparticles from Garlic Peel Target NF-κB and Redox Imbalance: A Novel Therapeutic Strategy Against Pyrogallol-Induced Hepatotoxicity in Rats

This study provides the first evidence that garlic peel-derived silver nanoparticles exert potent hepatoprotective effects through redox homeostasis restoration and modulation of the NF-κB signaling pathway. These findings highlight GPE-Ag as a promising, sustainable nanotherapeutic candidate for managing chemically induced liver injury.

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Publication Details

Journal
Nanomaterials
Published
2025-10-22
DOI
https://doi.org/10.3390/nano15211610
Citations
2
Primary Topic
Moringa oleifera research and applications
Type
article
Field-Weighted Citation Impact
3.50
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article

Green-Synthesized Silver Nanoparticles from Garlic Peel Target NF-κB and Redox Imbalance: A Novel Therapeutic Strategy Against Pyrogallol-Induced Hepatotoxicity in Rats

Duaa Althumairy
2 citations
Nanomaterials
Moringa oleifera research and applications
3.50
article

Green-Synthesized Silver Nanoparticles from Garlic Peel Target NF-κB and Redox Imbalance: A Novel Therapeutic Strategy Against Pyrogallol-Induced Hepatotoxicity in Rats

Duaa Althumairy
article en
2 citations

Abstract

This study provides the first evidence that garlic peel-derived silver nanoparticles exert potent hepatoprotective effects through redox homeostasis restoration and modulation of the NF-κB signaling pathway. These findings highlight GPE-Ag as a promising, sustainable nanotherapeutic candidate for managing chemically induced liver injury.

NanomaterialsVol. 15(21)
King Faisal University (SA)
Openalex Percentile: Top 7%
Moringa oleifera research and applications
3.50
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