MicroRNA whole-blood profiling in hospitalized patients with candidemia identified miR-125a-5p and miR-99b-5p as potential biomarkers for Candida albicans bloodstream infection
Overexpression of miR-125a-5p and miR-99b-5p in whole blood may discriminate C. albicans candidemia. These miRNAs are promising rapid biomarkers and targets for antifungal therapy.
Authors
- Cristina Carbonell (ORCID: https://orcid.org/0000-0002-6271-5111)
- Luís A. Corchete (ORCID: https://orcid.org/0000-0003-4577-8599)
- Carlos Gutiérrez-Cerrajero (ORCID: https://orcid.org/0000-0002-9698-2920)
- Daniel Salete-Granado (ORCID: https://orcid.org/0000-0002-3561-3507)
- Rogelio González‐Sarmiento (ORCID: https://orcid.org/0000-0002-2726-6795)
- Edgar Bernardo (ORCID: https://orcid.org/0000-0002-0500-9632)
- Silvio Ragozzino (ORCID: https://orcid.org/0000-0002-8100-2096)
- Hugo Guillermo Ternavasio‐de la Vega (ORCID: https://orcid.org/0000-0002-0500-6626)
- María Siller‐Ruiz
- Miguel Marcos (ORCID: https://orcid.org/0000-0003-1269-4487)
- Guadalupe Sabio (ORCID: https://orcid.org/0000-0002-2822-0625)
- Maura Rojas-Pirela (ORCID: https://orcid.org/0000-0002-4387-2613)
- F. Castaño-Romero
- Jorge Torres (ORCID: https://orcid.org/0000-0001-6853-9115)
- Rebeca Sánchez González
- María-Ángeles Pérez-Nieto (ORCID: https://orcid.org/0000-0003-0014-5165)
- María Inmaculada García‐García (ORCID: https://orcid.org/0000-0002-5804-2444)
- Mar�a Paz Vaquero-Herrero
- Alicia García-Señán
Institutions
- Broad Institute (US)
- Universidad de Salamanca (ES)
- University Hospital of Basel (CH)
- Spanish National Cancer Research Centre (ES)
- Instituto de Estudios de Ciencias de la Salud de Castilla y León (ES)
- Complejo Hospitalario de Salamanca (ES)
- Instituto de Investigación Biomédica de Salamanca (ES)
- Center for Cancer Research (US)
- Complejo Asistencial Universitario de Palencia (ES)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1016/j.ijid.2025.108148
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00