Sleep phenotypes of α-synucleinopathies and tauopathies with Parkinsonism
Distinct sleep phenotypes characterize neurodegenerative Parkinsonism with Syn or Tau. Pending pathological confirmation, our data suggests that neurodegeneration could affect sleep-wake regulatory brain systems in a proteinopathy-dependent manner. Sleep phenotypes hold promise as non-invasive biomarkers of Syn or Tau in Parkinsonism.
Authors
- Philipp O. Valko (ORCID: https://orcid.org/0000-0002-8435-1697)
- Esther Werth (ORCID: https://orcid.org/0000-0002-5099-3122)
- C. Nathan Marti (ORCID: https://orcid.org/0000-0002-6743-8512)
- Simon J. Schreiner (ORCID: https://orcid.org/0000-0002-5150-6066)
- Nils Briel (ORCID: https://orcid.org/0000-0002-4349-3277)
- Christian R. Baumann (ORCID: https://orcid.org/0000-0003-3417-1978)
- Heide Baumann‐Vogel
- Rositsa Poryazova (ORCID: https://orcid.org/0000-0003-1904-6802)
Institutions
- University of Zurich (CH)
- University Hospital of Zurich (CH)
Publication Details
- Journal
- Parkinsonism & Related Disorders
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1016/j.parkreldis.2025.108100
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39