MON-536 Association Between Periodontitis And Diabetes In Apparently Healthy Population: The Korean National Health And Nutrition Examination Survey 2013-2015

Abstract Disclosure: Y. Lyu: None. S. Kim: None. J. Kim: None. Aims We evaluated the relationship between periodontitis, undiagnosed prediabetes, and diabetes in apparently healthy individuals to assess the need for establishing periodontitis as a screening tool for diabetes. Materials and Methods Data from 7,335 participants enrolled in the Korean National Health and Nutrition Examination Survey between 2013 and 2015 were analyzed. Individuals were classified as diabetic, prediabetic, and normal based on fasting plasma glucose and glycated hemoglobin levels. Multivariate logistic regression analyses were used to identify the association of periodontal disease with undiagnosed prediabetes and diabetes within groups stratified by sex. Results The prevalence of undiagnosed prediabetes and diabetes was 20.1% and 2.7% in men, and 12.4% and 0.8% in women, respectively. After adjusting for confounding factors, including age, smoking, alcohol consumption, family income, education, place of residence, exercise, and frequency of tooth brushing, the multivariate logistic regression analysis revealed that men with periodontal disease had a higher risk of diabetes (odds ratio: 2.595; 95% confidence interval: 1.201-5.606), while no significant associations were found in women. Conclusions Individuals with periodontitis, especially men, have a higher risk of undiagnosed diabetes. Hence, screening for diabetes in adults with periodontal disease could lead to a decrease in the healthcare burdens associated with diabetes. Presentation: Monday, July 14, 2025